A pioneering study, “Towards a Plasmon-Based Biosensor Throughout a Thermo-Responsive Hydrogel,” has been published in ACS Applied Polymer Materials. Authored by Anne Parra, Óscar Ahumada, Andreas Thon, Valerio Pini, Julia Mingot, Elaine Armelin, Carlos Alemán, and Sonia Lanzalaco, this research represents a collaborative effort between Mecwins and the Polytechnic University of Catalunya (UPC) and introduces an innovative approach to biosensing using thermo-responsive hydrogels.
The study explores a custom-designed hydrogel composed of poly-N-isopropylacrylamide (PNIPAAm), a polymer known for its unique ability to react to temperature changes close to body temperature. This hydrogel serves as an adaptable substrate, dynamically controlling the movement of gold nanoparticles through its porous structure based on temperature variations. Crucially, it was shown that AVAC can effectively detect these gold nanoparticles within the hydrogel matrix, enhancing its ability to identify biomarkers.
This research lays important groundwork for future biosensors that combine the responsive and adaptive properties of hydrogels with high-precision plasmonic biosensing. Such advancements could drive significant improvements in diagnostic technologies and open new avenues in medical research.
